Chemical synthesis

Chemical Glass Reactor For A Chemical Reaction In Science Labora

Based on the current knowledge and our Team’s many years of experience in organic synthesis and development of active substance production processes, we offer the following R&D services:

  • synthesis of structurally complex organic compounds
  • synthesis of compound libraries
  • route scouting
  • development and optimisation of the synthesis process
  • development of analytical methods for controlling the course of reactions
  • scale-up
  • determination of critical process parameters
  • troubleshooting
  • technology transfer to the production facility
  • production of the active substance*
  • stability testing (initial or GMP*)
  • identification of impurities, synthesis and standard setting
  • preparation of the relevant sections of regulatory documents (Investigational Medicinal Product Dossier, Module 3)

When it comes to synthesis, we offer the following:

  • synthesis scale: from mg to kg
  • reactor volume: up to 20 l
  • multi-step syntheses
  • organometallic reactions
  • asymmetric synthesis
  • synthesis of heterocyclic compounds
  • synthesis of compound libraries
  • synthesis of compounds labelled with stable isotopes
  • development of flow processes
  • discovery and characterisation of polymorphs*

* services provided in cooperation with Business Partners