{"id":7836,"date":"2022-03-28T11:36:22","date_gmt":"2022-03-28T09:36:22","guid":{"rendered":"https:\/\/pikralida.eu\/drug-delivery-systems\/"},"modified":"2022-04-20T13:39:32","modified_gmt":"2022-04-20T11:39:32","slug":"drug-delivery-systems","status":"publish","type":"page","link":"https:\/\/pikralida.eu\/en\/drug-delivery-systems\/","title":{"rendered":"Drug Delivery Systems"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"7836\" class=\"elementor elementor-7836 elementor-7032\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5ed8b9ab elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5ed8b9ab\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-72888927\" data-id=\"72888927\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1f3181ad aux-appear-watch-animation aux-fade-in-up elementor-widget elementor-widget-aux_modern_heading\" data-id=\"1f3181ad\" data-element_type=\"widget\" data-widget_type=\"aux_modern_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<section class=\"aux-widget-modern-heading\">\n            <div class=\"aux-widget-inner\"><h1 class=\"aux-modern-heading-primary\"><\/h1><h1 class=\"aux-modern-heading-secondary\"><span class=\"aux-head-highlight\">Drug Delivery Systems<\/span><\/h1><div class=\"aux-modern-heading-divider\"><\/div><\/div>\n        <\/section>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a6d8a1e elementor-widget elementor-widget-spacer\" data-id=\"2a6d8a1e\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-7e5cd0d7\" data-id=\"7e5cd0d7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4cbd70cf elementor-section-full_width elementor-section-content-middle elementor-section-height-default elementor-section-height-default\" data-id=\"4cbd70cf\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-1f7b2d99\" data-id=\"1f7b2d99\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8d1c47f elementor-align-center bdt-navigation-type-arrows elementor-widget elementor-widget-bdt-slider\" data-id=\"8d1c47f\" data-element_type=\"widget\" data-widget_type=\"bdt-slider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"bdt-slider-8d1c47f\" class=\"bdt-slider bdt-arrows-align-center\" data-settings=\"{&quot;autoplay&quot;:{&quot;delay&quot;:2500},&quot;speed&quot;:2000,&quot;effect&quot;:&quot;fade&quot;,&quot;navigation&quot;:{&quot;nextEl&quot;:&quot;#bdt-slider-8d1c47f .bdt-navigation-next&quot;,&quot;prevEl&quot;:&quot;#bdt-slider-8d1c47f .bdt-navigation-prev&quot;},&quot;pagination&quot;:{&quot;el&quot;:&quot;#bdt-slider-8d1c47f .swiper-pagination&quot;,&quot;type&quot;:&quot;&quot;,&quot;clickable&quot;:&quot;true&quot;,&quot;dynamicBullets&quot;:false},&quot;scrollbar&quot;:{&quot;el&quot;:&quot;#bdt-slider-8d1c47f .swiper-scrollbar&quot;,&quot;hide&quot;:&quot;true&quot;}}\">\n\t\t\t<div class=\"swiper-carousel swiper\">\n\t\t\t\t\t\t<div class=\"swiper-wrapper\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1200\" height=\"800\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2021\/07\/system-dostarczania-lekow_tnOK.jpg\" class=\"bdt-cover\" alt=\"Slide#5\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1200\" height=\"800\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/sruby-ekstrudera_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide #1\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1200\" height=\"898\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/proces-ekstruzji_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide #2\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"796\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/ekstrudat_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide #3\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"798\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2021\/07\/ekstrudat-3_tnOK.jpg\" class=\"bdt-cover\" alt=\"Slide #4\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"865\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/IMGP3447_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide #6\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"798\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/IMGP3793_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide #7\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-position-z-index bdt-position-center\">\n\t\t\t\t\t\t<div class=\"bdt-arrows-container bdt-slidenav-container\">\n\t\t\t\t\t\t\t<a href=\"\" class=\"bdt-navigation-prev bdt-slidenav-previous bdt-icon bdt-slidenav\">\n\t\t\t\t\t\t\t\t<i class=\"ep-icon-arrow-left-0\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<a href=\"\" class=\"bdt-navigation-next bdt-slidenav-next bdt-icon bdt-slidenav\">\n\t\t\t\t\t\t\t\t<i class=\"ep-icon-arrow-right-0\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-151636b8\" data-id=\"151636b8\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2f0f0358 elementor-widget elementor-widget-text-editor\" data-id=\"2f0f0358\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p style=\"text-align: left;\">Innovative formulations of medicinal products are essential when it comes to the development of innovative and effective treatment methods. The most common challenges faced by modern drug therapy include the development of formulations for low solubility substances and the development of delivery systems for drugs that modulate the release profile of the active substance. <br \/>At Pikralida, we have set up an R&amp;D laboratory for super generic drugs, where we use modern technologies such as <a href=\"https:\/\/pikralida.eu\/en\/hot-melt-extrusion\/\">hot melt extrusion<\/a> that make it possible to solve problems associated with the solubility and bioavailability of active substances. The use of this technology also allows for designing and developing various drug forms, including forms with a modified release profile of the active substance, e.g. sustained-release tablets or implants.<\/p><h3>Hot Melt Extrusion<\/h3><p>The <a href=\"https:\/\/pikralida.eu\/en\/hot-melt-extrusion\/\">hot melt extrusion<\/a> (HME) technique is a modern and efficient technological process used in the pharmaceutical industry to obtain a solid drug formulation. The method involves dispersing the therapeutical substance in a polymer melt, followed by the extrusion of the resulting mixture. For the HME process to be viable, the polymers used in the hot melt extrusion process need to have suitable thermoplastic properties and to be thermally stable at extrusion temperatures. Plasticization of the raw material due to high temperature and pressure, combined with it passing through a channel with an appropriate profile, yield a product of uniform shape and density. The final form of the drug may be formed directly from the extrudate obtained (such as implants) or by combining it with selected excipients (such as tablets).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Drug Delivery Systems Innovative formulations of medicinal products are essential when it comes to the development of innovative and effective treatment methods. The most common challenges faced by modern drug therapy include the development of formulations for low solubility substances and the development of delivery systems for drugs that modulate the release profile of the [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7836","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/pages\/7836","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/comments?post=7836"}],"version-history":[{"count":0,"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/pages\/7836\/revisions"}],"wp:attachment":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/media?parent=7836"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}