{"id":7744,"date":"2022-04-19T14:14:06","date_gmt":"2022-04-19T12:14:06","guid":{"rendered":"https:\/\/pikralida.eu\/development-of-formulations-of-medicinal-products\/"},"modified":"2022-04-19T14:14:09","modified_gmt":"2022-04-19T12:14:09","slug":"development-of-formulations-of-medicinal-products","status":"publish","type":"page","link":"https:\/\/pikralida.eu\/en\/development-of-formulations-of-medicinal-products\/","title":{"rendered":"Development of formulations of medicinal products"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"7744\" class=\"elementor elementor-7744 elementor-7223\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-28ffe098 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"28ffe098\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-4275fdcb\" data-id=\"4275fdcb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-622ee2ce aux-appear-watch-animation aux-fade-in-up elementor-widget elementor-widget-aux_modern_heading\" data-id=\"622ee2ce\" data-element_type=\"widget\" data-widget_type=\"aux_modern_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<section class=\"aux-widget-modern-heading\">\n            <div class=\"aux-widget-inner\"><h1 class=\"aux-modern-heading-primary\"><\/h1><h3 class=\"aux-modern-heading-secondary\"><span class=\"aux-head-highlight\">Development of formulations of medicinal products<\/span><\/h3><div class=\"aux-modern-heading-divider\"><\/div><\/div>\n        <\/section>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-eeda182 elementor-widget elementor-widget-spacer\" data-id=\"eeda182\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2b57d822\" data-id=\"2b57d822\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6aa91360 elementor-section-full_width elementor-section-content-middle elementor-section-height-default elementor-section-height-default\" data-id=\"6aa91360\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-73d23633\" data-id=\"73d23633\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7eae3636 elementor-align-center bdt-navigation-type-arrows elementor-widget elementor-widget-bdt-slider\" data-id=\"7eae3636\" data-element_type=\"widget\" data-widget_type=\"bdt-slider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"bdt-slider-7eae3636\" class=\"bdt-slider bdt-arrows-align-center\" data-settings=\"{&quot;autoplay&quot;:{&quot;delay&quot;:2500},&quot;speed&quot;:2000,&quot;effect&quot;:&quot;fade&quot;,&quot;navigation&quot;:{&quot;nextEl&quot;:&quot;#bdt-slider-7eae3636 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bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1200\" height=\"803\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/AdobeStock_7749647_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide #2\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1200\" height=\"934\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/IMGP3436_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide #3\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"782\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/IMGP3482_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide #4\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"619\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/tabletki-1_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide#5\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"798\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/IMGP3657_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide #6\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"798\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/tabletka_tnWEB-1.jpg\" class=\"bdt-cover\" alt=\"Slide #7\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"619\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/tabletki-1_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide #8\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slide-text\">Slide Content<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"804\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/IMGP3543_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide #9\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slide-text\">Slide Content<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"bdt-slide-item swiper-slide left\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slider-image-wrapper\">\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"619\" src=\"https:\/\/pikralida.eu\/wp-content\/uploads\/2022\/03\/tabletki-1_tnWEB.jpg\" class=\"bdt-cover\" alt=\"Slide Title\" data-bdt-cover=\"1\" \/>\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"bdt-slide-desc bdt-position-large bdt-position-center bdt-position-z-index\">\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-slide-text\">Slide Content<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bdt-position-z-index bdt-position-center\">\n\t\t\t\t\t\t<div class=\"bdt-arrows-container bdt-slidenav-container\">\n\t\t\t\t\t\t\t<a href=\"\" class=\"bdt-navigation-prev bdt-slidenav-previous bdt-icon bdt-slidenav\">\n\t\t\t\t\t\t\t\t<i class=\"ep-icon-arrow-left-0\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<a href=\"\" class=\"bdt-navigation-next bdt-slidenav-next bdt-icon bdt-slidenav\">\n\t\t\t\t\t\t\t\t<i class=\"ep-icon-arrow-right-0\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-4ffa9a37\" data-id=\"4ffa9a37\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-74c350e2 elementor-widget elementor-widget-text-editor\" data-id=\"74c350e2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3>Based on the current knowledge and our Team&#8217;s many years of experience in pharmaceutical form design and development as well as pharmaceutical analysis, we provide comprehensive services in the field of research and development of medicinal products.<\/h3><p>We develop the following:<\/p><ul><li>formulations of innovative investigational medicinal products for clinical trials<\/li><li>formulations of fixed-dose combinations<\/li><li>modified release formulations<\/li><li>drug delivery systems<\/li><li>modified release formulations<\/li><li>placebo formulations for clinical trials<\/li><\/ul><p>We have a wealth of experience in the development of solid (tablets, powders, granules), semi-solid and liquid forms of medicinal products. As regards the most common drug form, namely tablets, we develop tablets with various release profiles, as well as ODT ones.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7a9cdf69 elementor-section-full_width elementor-section-content-middle elementor-section-height-default elementor-section-height-default\" data-id=\"7a9cdf69\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5c60787c\" data-id=\"5c60787c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-627fe4a0 elementor-widget elementor-widget-text-editor\" data-id=\"627fe4a0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3>Depending on the requirements of our Clients, projects include the following steps:<\/h3><ul><li>selection of suppliers of active substances<\/li><li>preformulation studies<\/li><li>formulation development<\/li><li>increasing the solubility of active substances, e.g. by using a hot melt <a href=\"https:\/\/pikralida.eu\/en\/hot-melt-extrusion\/\">extrusion<\/a> process in order to achieve amorphisation of the active substance<\/li><li>optimisation of the technology developed and scale-up<\/li><li>technology transfer to the production facility<\/li><li>manufacturing of the (investigational) medicinal product, placebo in the GMP standard*<br>stability testing (initial and GMP*)<\/li><li>preparation of the relevant sections of regulatory documents (Investigational Medicinal Product Dossier, Module 3)<\/li><li>production facility audits<\/li><\/ul><p>We implement all projects in accordance with current knowledge and regulatory requirements, to meet the highest standard of research.<\/p><p>We also offer development of formulations for in-vitro and in-vivo studies, as well as formulations for dietary supplements, special purpose foods and cosmetics.<\/p><p>* services provided in cooperation with Business Partners<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Development of formulations of medicinal products Slide Content Slide Content Slide Content Based on the current knowledge and our Team&#8217;s many years of experience in pharmaceutical form design and development as well as pharmaceutical analysis, we provide comprehensive services in the field of research and development of medicinal products. We develop the following: formulations of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7744","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/pages\/7744","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/comments?post=7744"}],"version-history":[{"count":0,"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/pages\/7744\/revisions"}],"wp:attachment":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/media?parent=7744"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}