{"id":7741,"date":"2022-04-19T14:01:34","date_gmt":"2022-04-19T12:01:34","guid":{"rendered":"https:\/\/pikralida.eu\/chemical-synthesis\/"},"modified":"2022-05-19T12:07:37","modified_gmt":"2022-05-19T10:07:37","slug":"chemical-synthesis","status":"publish","type":"page","link":"https:\/\/pikralida.eu\/en\/chemical-synthesis\/","title":{"rendered":"Chemical synthesis"},"content":{"rendered":"\t\t
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<\/h1>

Chemical synthesis<\/span><\/h3>
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Based on the current knowledge and our Team’s many years of experience in organic synthesis and development of active substance production processes, we offer the following R&D services:<\/h3>
  • synthesis of structurally complex organic compounds<\/li>
  • synthesis of compound libraries<\/li>
  • route scouting<\/li>
  • development and optimisation of the synthesis process<\/li>
  • development of analytical methods for controlling the course of reactions<\/li>
  • scale-up<\/li>
  • determination of critical process parameters<\/li>
  • troubleshooting<\/li>
  • technology transfer to the production facility<\/li>
  • production of the active substance*<\/li>
  • stability testing (initial or GMP*)<\/li>
  • identification of impurities, synthesis and standard setting<\/li>
  • preparation of the relevant sections of regulatory documents (Investigational Medicinal Product Dossier, Module 3)<\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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    When it comes to synthesis, we offer the following:<\/h3>
    • synthesis scale: from mg to kg<\/li>
    • reactor volume: up to 20 l<\/li>
    • multi-step syntheses<\/li>
    • organometallic reactions<\/li>
    • asymmetric synthesis<\/li>
    • synthesis of heterocyclic compounds<\/li>
    • synthesis of compound libraries<\/li>
    • synthesis of compounds labelled with stable isotopes<\/li>
    • development of flow processes<\/li>
    • discovery and characterisation of polymorphs*<\/li><\/ul>

      * services provided in cooperation with Business Partners<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

      Chemical synthesis Based on the current knowledge and our Team’s many years of experience in organic synthesis and development of active substance production processes, we offer the following R&D services: synthesis of structurally complex organic compounds synthesis of compound libraries route scouting development and optimisation of the synthesis process development of analytical methods for controlling […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7741","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/pages\/7741","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/comments?post=7741"}],"version-history":[{"count":0,"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/pages\/7741\/revisions"}],"wp:attachment":[{"href":"https:\/\/pikralida.eu\/en\/wp-json\/wp\/v2\/media?parent=7741"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}